Rak debelog crijeva Colorectal Cancer

Zaraza virusom humane imunodeficijencije i tuberkuloza crijeva: prikaz bolesnika

Opisujemo tridesetdvogodi{njeg bolesnika zara`enog HIV-om koji se razbolio pet mjeseci prije prijema u Kliniku s progresivnim mr{avljenjem, febrilitetom i dijarejom. Zadnja 4 dana prije prijama osjetio je ja~e bolove u trbuhu. U ~asu prijama u bolnicu bio je afebrilan, orijentiran, usporen, blijed, afoni~an, klonuo, kahekti~an i nepokretan. Abdomen je bio mekan, difuzno lagano osjetljiv na palp...

Author's response to reviews Title:The induction of activating transcription factor 3 (ATF3) contributes to anti-cancer activity of Abeliophyllum distichum Nakai in human colorectal cancer cells Authors:

Anti-Proliferative Effect of Naringenin through p38-Dependent Downregulation of Cyclin D1 in Human Colorectal Cancer Cells

Naringenin (NAR) as one of the flavonoids observed in grapefruit has been reported to exhibit an anti-cancer activity. However, more detailed mechanism by which NAR exerts anti-cancer properties still remains unanswered. Thus, in this study, we have shown that NAR down-regulates the level of cyclin D1 in human colorectal cancer cell lines, HCT116 and SW480. NAR inhibited the cell proliferation ...

The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb.

Rak is a nuclear tyrosine kinase containing Src homology 2 and 3 domains at its NH2 terminus. We report here that the retinoblastoma tumor susceptibility gene product pRb associates with Rak in vivo and in vitro. Rak binds in the A/B pocket region of pRb, a region that is frequently mutated in human cancer, during the G1 and S phases of the cell cycle. Furthermore, Rak expression is elevated in...

Relevance of the viral RAK alpha gene in diagnosis of malignant versus nonmalignant tumors of the ovary and uterus.

Human immunodeficiency virus type 1 (HIV-1)-like antigens RAK (named after the inventor E. M. Rakowicz) p120, p42, and p25, as well as HIV-1-like segments of cancer DNA (RAK gene alpha), have been found before in breast and prostate cancers. The present study focused on determining the value of markers RAK in the diagnosis and prognosis of gynecological cancer. Expression of RAK antigens in ova...